Study of onset, progression and treatment of hematological and solid tumors, focusing on chronic lymphocytic leukemia, glioma, neuroblastoma, colorectal, pancreatic, ovarian and breast cancer

The project aims to investigate the physiopathological roles of a class of emerging genes causative for neuronal functional and morphological alterations that impact on cellular development, synaptic function and behavior. The activities related to this research topic are the study of proteins involved in the physiopathological mechanisms that regulate synaptic vesicle biogenesis, trafficking and degradation and the impact of dysregulation of presynaptic physiology in brain disorders