Study of onset, progression and treatment of hematological and solid tumors, focusing on chronic lymphocytic leukemia, glioma, neuroblastoma, colorectal, pancreatic, ovarian and breast cancer

Hematopoietic Stem Cell Transplantation (HSCT) and immunotherapy are important instruments to fight hematological malignancies and solid tumors. Immunotherapeutic approaches include the use of monoclonal antibodies (mAbs) targeting tumor-associated antigens or blocking immune checkpoints (ICB), and chimeric antigen receptor (CAR)-engineered T or NK cells.