Development of immune-mediated approaches for anti-cancer therapy

Hematopoietic Stem Cell Transplantation (HSCT) and immunotherapy are important instruments to fight hematological malignancies and solid tumors. Immunotherapeutic approaches include the use of monoclonal antibodies (mAbs) targeting tumor-associated antigens or blocking immune checkpoints (ICB), and chimeric antigen receptor (CAR)-engineered T or NK cells. This research area aims at increasing the efficiency and decreasing the side effects of these very promising approaches

The reconstitution of the immune system in patients receiving HSCT 


The analysis of patients’ immune response before and following immunotherapy 


The development of new, personalized, immunotherapeutic approaches 


Last update 8 July 2022