Study of onset, progression and treatment of hematological and solid tumors, focusing on chronic lymphocytic leukemia, glioma, neuroblastoma, colorectal, pancreatic, ovarian and breast cancer

To study physiologically relevant in vitro 3D models as platforms for a dynamic comprehension of physiopathology, providing a more reliable model in “drug discovery” that mimics the in vivo tissue morphology and microenvi

Cancer treatments are nowadays quite effective in the first istance, but very often recurrent resistance phenomena arise with inauspicious prognostic outcomes. Study the adaptive cellular responses and the molecular mechanisms induced by short- and long-term treatments with anticancer drugs in different human cancer cells is useful in order to identify new potential molecular targets.