The detection of biomarkers in body fluids has major advantages over the use of tissue markers, which most often require invasive biopsies that can be difficult to perform and potentially dangerous. Discriminating between cargoes associated with extracellular vesicles in body fluids using different approaches could provide insight into disease staging.
Engineered extracellular vesicles isolated from plasma or red blood cells as tools for the delivery of bioactive molecules to specific sites
Scientists: Tasso R.
Phenotypic profiling and functional characterization of extracellular vesicles isolated from human amniotic fluid samples from different gestational stage as theranostic tools and paracrine therapeutic candidates in preclinical models of ischemic and inflammatory disease
Scientists: Bollini S.
Phenotypic profiling and functional characterization of extracellular vesicles isolated from human cerebrospinal fluid samples from Alzheimer's disease patients
Scientists: Bollini S.
Phenotypic and functional characterization of extracellular vesicles isolated from plasma/serum of oncologic patients (triple negative breast cancer, lung cancer, ERBB2-positive breast cancer) as diagnostic tools
Scientists: Gentili C., Tasso R.
Phenotypic and quantitative profiling of extracellular vesicles and lipid-rich vesicular subtypes (spheresomes) released by tumor cells under stress or therapeutic conditions, and their potential use as diagnostic or theranostic biomarkers
Scientists: Cortese K.