Glycobiology

Glycosylation is the post-translational modification of proteins that gives the most variability to them. The glycosylation of proteins is a very complex process that involves a great number of enzymes and reactions. Moreover, glycosylation is involved in many processes of cell life from signaling to single enzyme activity. The study of protein glycosylation can give important information to understand many cellular processes and to develop new therapeutic approaches

 


Identification and characterization of enzymes involved in the glycosylation pathways of human and non-human pathogens and characterization of their glycan structures

 

Scientists:  Tonetti M. 

Keywords:  nucleotide-sugars, glycosyltransferases, complex glycans, glycobiology

 

 


Identification of human TGDS role in Catel-Manzke disease by in vitro human cells models and in vivo zebrafish experimental system

 

Scientists:  Tonetti M. 

Keywords:  Catel-Manzke, TGDS, zebrafish, Pierre-Robin sequence, glycobiology

 


Qualitative and quantitative characterization of serum glycoproteins and evaluation of immunoglobulin role in the treatment and progression of non autoimmune kidney diseases

 

Scientists:  Bruschi M.

Keywords: proteomics, glycoproteins, immunoglobulins, lectins, kidney disease

Last update 25 January 2023