Identification of biomarkers associated with the onset or progression of different types of diseases.
Genetic barcoding and Next Generation Sequencing (NGS) to evaluate sensitivity and efficiency of diagnosis by liquid biopsy in triple negative breast cancer and high grade gliomas
Personale coinvolto: Malatesta P., Ceresa D.
Parole chiave: NGS, genetic barcoding, liquid biospy, biomarkers
Developing high-throughput methods for the clinical implementation of drug screenings on single patients and the design of combined therapies
Personale coinvolto: Ceresa D.
Parole chiave: genetic barcoding, personalized medicine, drug screening
Identification of new biomarkers in the sera of patients affected by cardiovascular and autoimmune diseases
Personale coinvolto: Furfaro A.L., Nitti M., Traverso N.
Parole chiave: heme oxygenase-1, monocytes, macrophages, aneurism, autoimmune diseases
Identification and validation of new biomarkers associated with sepsis
Personale coinvolto: Furfaro A.L., Traverso N.
Parole chiave: sepsi, procalcitonina, presepsina, MR-proADM, biomarcatori
Characterization of proteins, metabolites and lipids profile of main biological fluids such as serum, plasma, urine, cerebrospinal fluid and their extracellular vesicles as source of diagnostic and prognostic biomarkers
Scientists: Bruschi M.
Keywords: biomarkers, proteomics, metabolomics, lipidomics, secretome
Evaluation of autoantibodies' role in the pathogenesis and progression of renal damage in patients affected by primitive glomerulonephritis
Scientists: Bruschi M.
Keywords: proteomics, autoantibodies, primitive glomerulonephritis, diagnostic tools
Proteome profile characterization of extracellular vesicles released from cell culture under different conditions and evaluation of their role in the intercellular communication and regulation of cell microenvironment
Scientists: Bruschi M.
Keywords: biomarkers, proteomics, secretome, extracellular vesicles