Human Innate Lymphoid Cells (ILCs)

Innate Lymphoid Cells (ILCs) are a recently identified family of innate immune cells. Their accurate analysis allows the understanding of how they contribute to host defense, tissue morphogenesis, homeostasis and repair, and pathological conditions such as immunodeficiencies, autoinflammatory diseases, and autoimmunity. The main interests of this research area are Natural Killer (NK) cells, cytotoxic innate lymphoid cells circulating in the blood and detectable in tissues and characterized by the ability to efficiently kill tumor or virus-transformed cells


The differentiation, education, and function of NK cells with a spotlight on the generation of NK cells endowed with adaptive features

 


The inflammatory and anti-inflammatory factors, and small non-coding RNA (miRNA) modulating NK cell receptor expression and function

 

Last update 8 July 2022